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Fosaprepitant dimeglumine(EMEND) powder

///Fosaprepitant dimeglumine(EMEND) powder

Fosaprepitant dimeglumine(EMEND) powder

Fosaprepitant Dimeglumine powder is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.

Additional information

CAS No.

265121-04-8

Molecular Formula

C23H22F7N4O6P.2C7H17NO5

Molecular Weight

1004.83 g*mol-1

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