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Entecavir hydrate powder

///Entecavir hydrate powder

Entecavir hydrate powder

Entecavir hydrate powder is a potent deoxyguanosine nucleoside analog with antiviral activity selective for hepadnaviruses (EC50 = 3.7 nM against the hepatitis B virus (HBV) in cultured 2.2.15 liver cells). In vitro, the active intracellular form of entecavir, Entecavir hydrate powder triphosphate, demonstrates a higher binding affinity for HBV DNA polymerase than the natural guanosine triphosphate substrate and effectively inhibits HBV DNA replication at 3 stages in the replication pathway: priming, reverse transcription, and DNA-dependent DNA synthesis.

Additional information

CAS No.

209216-23-9

Molecular Formula

C12H17N5O4

Molecular Weight

295.29 g*mol-1

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